BBK07 Immunodominant Peptides as Serodiagnostic Markers of Lyme Disease
نویسندگان
چکیده
منابع مشابه
Advances in Serodiagnostic Testing for Lyme Disease Are at Hand.
The cause of Lyme disease, Borrelia burgdorferi, was discovered in 1983. A 2-tiered testing protocol was established for serodiagnosis in 1994, involving an enzyme immunoassay (EIA) or indirect fluorescence antibody, followed (if reactive) by immunoglobulin M and immunoglobulin G Western immunoblots. These assays were prepared from whole-cell cultured B. burgdorferi, lacking key in vivo express...
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Chemokines and cytokines are key signaling molecules that orchestrate the trafficking of immune cells, direct them to sites of tissue injury and inflammation and modulate their states of activation and effector cell function. We have measured, using a multiplex-based approach, the levels of 58 immune mediators and 7 acute phase markers in sera derived from of a cohort of patients diagnosed with...
متن کاملImproved serodiagnostic testing for Lyme disease: results of a multicenter serologic evaluation.
The diverse clinical manifestations of Lyme disease (1-3) have led to frequent confusion in clinical diagnosis, a confusion compounded by problems in the accuracy and precision of diagnostic serologic tests (4-11) and the difficulty of isolating the causative organism (12-14), Borrelia burgdorferi. In 1990, more than 20 commercially prepared serologic test kits for Lyme disease were being sold ...
متن کاملa case of lyme disease (lyme borreliosis)
while an important infectious disease in the united states and eurasia, lyme disease is rare in iran. we present a 9-year old boy admitted in children’s medical center in december 2001 with final diagnosis of lyme disease. on admission he showed arthritis and a history of previous skin lesions. serologic examination including enzyme–linked immunosorbent assay and western blot was positive for l...
متن کاملReport of a case of Lyme disease in Mazandaran
Lyme disease is caused by the spirochete Borrelia burgdorferi. Depending on the stage of illness, infection may be limited to the skin or involve the cardiac, nervous and musculoskeletal systems. Herein, we report a case of Lyme disease in a 23-year-old woman from North of Iran (Mazandaran) in early-localized stage of erythema chronicum migrans. The diagnosis was confirmed by the presence of se...
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ژورنال
عنوان ژورنال: Clinical and Vaccine Immunology
سال: 2011
ISSN: 1556-6811,1556-679X
DOI: 10.1128/cvi.00461-10